Tuesday 6th November
08:30
Badge Collection & Coffee
09:30
Introduction & welcome from the Chairs
09:40
Session 1: Co-morbidities
The role of comorbidities in multiple sclerosis
Dr Ruth Ann Marrie
Departments of Internal Medicine and Community Health Sciences, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Canada
The role of comorbidities in multiple sclerosis
Dr Ruth Ann Marrie
Departments of Internal Medicine and Community Health Sciences, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Canada
10:20
The potential role of statins in treatment of multiple sclerosis
Professor John Greenwood
Hugh Davson Professor of Biomedical Research and Head of the Department of Cell Biology, Institute of Ophthalmology, University College London, UK
Professor John Greenwood
Hugh Davson Professor of Biomedical Research and Head of the Department of Cell Biology, Institute of Ophthalmology, University College London, UK
11:00
Coffee Break
11:25
Smoking and multiple sclerosis
Dr Anna Hedström
Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
Dr Anna Hedström
Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
12:05
Exercise intervention in the management of MS
Professor Rob Motl
Professor and Director of Research, Department of Physical Therapy; Associate Director of Research, UAB|Lakeshore Collaborative; Associate Director, UAB Center for Exercise Medicine; Director, REACT Mobile Technology Laboratory; Co-Director, Exercise Neuroscience Research Laboratory, The University of Alabama at Birmingham, AL USA
Professor Rob Motl
Professor and Director of Research, Department of Physical Therapy; Associate Director of Research, UAB|Lakeshore Collaborative; Associate Director, UAB Center for Exercise Medicine; Director, REACT Mobile Technology Laboratory; Co-Director, Exercise Neuroscience Research Laboratory, The University of Alabama at Birmingham, AL USA
12:45
Lunch
13:45
Session 2: Cellular therapies in the treatment of Multiple Sclerosis
Haemopoietic stem cell transplantation in the management of multiple sclerosis
Professor Richard K. Burt
Chief of Immunotherapy and Autoimmune Diseases & Professor of Medicine, Division of Immunotherapy, Northwestern University Feinberg School of Medicine, Chicago, IL, USA
Haemopoietic stem cell transplantation in the management of multiple sclerosis
Professor Richard K. Burt
Chief of Immunotherapy and Autoimmune Diseases & Professor of Medicine, Division of Immunotherapy, Northwestern University Feinberg School of Medicine, Chicago, IL, USA
14:25
Mesenchymal stem cell transplantation in MS
Professor Dimitrios Karussis
Director of the Hadassah Unit of Neuroimmunology and cell therapies, Department of Neurology and Agnes-Ginges Centre for Neurogenetics, Hadassah-Hebrew University Medical Organisation, Jerusalem, Israel
Professor Dimitrios Karussis
Director of the Hadassah Unit of Neuroimmunology and cell therapies, Department of Neurology and Agnes-Ginges Centre for Neurogenetics, Hadassah-Hebrew University Medical Organisation, Jerusalem, Israel
15:05
Coffee Break
15:30
Is B-cell depletion sufficient as a treatment strategy in MS?
Professor Fredrik Piehl
Professor of Clinical Neuroscience, Department of Clinical Neuroscience, The Karolinska Institutet, Stockholm, Sweden
Professor Fredrik Piehl
Professor of Clinical Neuroscience, Department of Clinical Neuroscience, The Karolinska Institutet, Stockholm, Sweden
16:10
Are current patient expectations of cellular treatments realistic?
Professor Gianvito Martino
Scientific Director, San Raffaele Scientific Institute; Professor of Experimental Biology, Vita Salute San Raffaele University, Milan, Italy
Professor Gianvito Martino
Scientific Director, San Raffaele Scientific Institute; Professor of Experimental Biology, Vita Salute San Raffaele University, Milan, Italy
16:50
Debate: 'Neurologists should offer patients radiologically isolated syndrome disease-modifying therapies'
For
Professor Darin Okuda
Director of the MS and Neuroimmunology Imaging Program; Deputy Director of the MS Program and Clinical Center for MS, UT Southwestern Medical Center, Dallas, TX, USA
For
Professor Darin Okuda
Director of the MS and Neuroimmunology Imaging Program; Deputy Director of the MS Program and Clinical Center for MS, UT Southwestern Medical Center, Dallas, TX, USA
17:50
Close
Wednesday 7th November
09:30
Session 3: De-risking multiple sclerosis treatments in clinical practice
Derisking lymphopenia in the management of MS
Professor Alasdair Coles
Professor of Neuroimmunology, Department of Clinical Neurosciences (A.J.C., D.A.S.C.), University of Cambridge, UK
Derisking lymphopenia in the management of MS
Professor Alasdair Coles
Professor of Neuroimmunology, Department of Clinical Neurosciences (A.J.C., D.A.S.C.), University of Cambridge, UK
10:10
Managing pharmacovigilance burden in MS
Associate Professor Stephen Reddel
Staff Specialist Neurologist, Concord Repatriation & General Hospital Sydney; Consultant Neurologist The Brain & Mind Centre, University of Sydney, Australia
Associate Professor Stephen Reddel
Staff Specialist Neurologist, Concord Repatriation & General Hospital Sydney; Consultant Neurologist The Brain & Mind Centre, University of Sydney, Australia
10:50
Coffee Break
11:15
PML and multiple sclerosis
Professor David Clifford
Professor of Neurology and Medicine & Melba and Forest Seay Professor of Clinical Neuropharmacology in Neurology, Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA
Professor David Clifford
Professor of Neurology and Medicine & Melba and Forest Seay Professor of Clinical Neuropharmacology in Neurology, Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA
11:55
A practical guide to treatment cessation
Dr Robert Bermel
Staff Neurologist and Director, Mellen Center for Multiple Sclerosis; Neurological Institute, Cleveland Clinic
Dr Robert Bermel
Staff Neurologist and Director, Mellen Center for Multiple Sclerosis; Neurological Institute, Cleveland Clinic
12:35
Lunch
13:30
Session 4: Progressive multiple sclerosis & hand function
Hand function as an outcome measure in clinical trials
Professor Dr Bernard Uitdehaag
Professor of Neurology, Chair of the Department of Neurology, Director of the MS Center Amsterdam, VU University Medical Center, Amsterdam, The Netherlands
Hand function as an outcome measure in clinical trials
Professor Dr Bernard Uitdehaag
Professor of Neurology, Chair of the Department of Neurology, Director of the MS Center Amsterdam, VU University Medical Center, Amsterdam, The Netherlands
14:10
Designing disease modifying therapy trials in more advanced disease
Professor Gary Cutter
Professor of Biostatistics, University of Alabama at Birmingham, School of Public Health, Department of Biostatistics, Birmingham, AL, USA
Professor Gary Cutter
Professor of Biostatistics, University of Alabama at Birmingham, School of Public Health, Department of Biostatistics, Birmingham, AL, USA
14:50
Coffee Break
15:15
Using MRI as an outcome measure in progressive MS
Professor Olga Ciccarelli
Professor of Neurology, Department of Neuroinflammation, UCL Institute of Neurology, University College London, UK
Professor Olga Ciccarelli
Professor of Neurology, Department of Neuroinflammation, UCL Institute of Neurology, University College London, UK
15:55
The identification of potential treatment targets in advancing MS
Professor Bruno Stankoff
Professor of Neurology at Pierre and Marie Curie University, Paris, France
Professor Bruno Stankoff
Professor of Neurology at Pierre and Marie Curie University, Paris, France
16:35
Close
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