Monday 20th November
From 08:00
Registration and Coffee
09:00
Introduction and Welcome from the Chairs
09:10
Cellular immunology and its relevance to MS
B-cells subsets and their role in MS
Professor Amit Bar-Or
Center for Neuroinflammation and Experimental Therapeutics, University of Pennsylvania, Philadelphia, PA USA
B-cells subsets and their role in MS
Professor Amit Bar-Or
Center for Neuroinflammation and Experimental Therapeutics, University of Pennsylvania, Philadelphia, PA USA
09:50
NK-cells as a therapeutic target in MS
Professor Dr Roland Martin
University of Zurich, Zurich, Switzerland
Professor Dr Roland Martin
University of Zurich, Zurich, Switzerland
10:30
Coffee Break
10:55
Role of T-regs in the treatment of MS
Dr Joanne Jones
Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK
Dr Joanne Jones
Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK
12:15
Lunch
13:15
Progressive Multiple Sclerosis
Therapeutic lag in progressive MS trials
Professor Maria Pia Sormani
Department of Health Sciences, University of Genoa, Italy
Therapeutic lag in progressive MS trials
Professor Maria Pia Sormani
Department of Health Sciences, University of Genoa, Italy
13:55
How to define secondary progressive MS
Dr Tomas Kalincik
Melbourne Brain Centre, Royal Melbourne Hospital, Melbourne, Australia
Dr Tomas Kalincik
Melbourne Brain Centre, Royal Melbourne Hospital, Melbourne, Australia
14:35
Coffee Break
15:00
Energetics and its role in progressive MS
Dr Don Mahad
Anne Rowling Regenerative Neurology Clinic, The University of Edinburgh, Edinburgh, UK
Dr Don Mahad
Anne Rowling Regenerative Neurology Clinic, The University of Edinburgh, Edinburgh, UK
15:40
The expanding MS lesion as a treatment target in MS
Dr Daniel Reich
Neuroimmunology Branch, National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD, USA
Dr Daniel Reich
Neuroimmunology Branch, National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD, USA
16:20
Debate: "To B or not T-B: that is the question"; the key pathogenic cell in MS is a B-cell and is independent of antigen presentation to T-cells
For
Professor David Baker
Centre for Neuroscience and Trauma, Blizard Institute, Barts and The London School of Medicine and Dentistry, London, UK
For
Professor David Baker
Centre for Neuroscience and Trauma, Blizard Institute, Barts and The London School of Medicine and Dentistry, London, UK
16:20
vs
Against
Prof. Dr. med. Heinz Wiendl
Department of Neurology Universität Münster, Albert-Schweitzer-Campus 1 Münster, Germany
Against
Prof. Dr. med. Heinz Wiendl
Department of Neurology Universität Münster, Albert-Schweitzer-Campus 1 Münster, Germany
17:00
Scientific sessions close
Tuesday 21st November
09:00
Progressive Multiple Sclerosis contd.
Motor-sensory prognostic paradox in MS
Professor Gavin Giovannoni
Barts and The London School of Medicine and Dentistry, London, UK
Motor-sensory prognostic paradox in MS
Professor Gavin Giovannoni
Barts and The London School of Medicine and Dentistry, London, UK
09:40
Disease improvement in progressive MS trials
Dr Bruce Cree
Department of Neurology, UCSF School of Medicine, San Francisco, CA, USA
Dr Bruce Cree
Department of Neurology, UCSF School of Medicine, San Francisco, CA, USA
10:20
Coffee Break
10:45
Epidemiology of Multiple Sclerosis
The case for EBV vaccination to prevent MS
Professor Alberto Ascherio
Department of Nutrition, Department of Epidemiology, Harvard T.H. Chan School of Public Health, Cambridge, MA, USA
The case for EBV vaccination to prevent MS
Professor Alberto Ascherio
Department of Nutrition, Department of Epidemiology, Harvard T.H. Chan School of Public Health, Cambridge, MA, USA
11:25
Vitamin D as a disease-modifying treatment for MS
Dr Joost Smolders
Canisius Wilhelmina Ziekenhuis Nijmegen, The Netherlands
Dr Joost Smolders
Canisius Wilhelmina Ziekenhuis Nijmegen, The Netherlands
12:05
Lunch
13:00
Epidemiology of Multiple Sclerosis contd.
Lifestyle & environmental factors and their interactions with multiple sclerosis risk genes
Professor Tomas Olsson
Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
Lifestyle & environmental factors and their interactions with multiple sclerosis risk genes
Professor Tomas Olsson
Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
13:40
TNF-alpha and what it tells us about MS
Professor Lars Fugger
The Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, UK
Professor Lars Fugger
The Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, UK
14:20
Sex hormones in MS
Dr Riley Bove
UCSF School of Medicine, Department of Neurology, UCSF, San Francisco, CA, USA
Dr Riley Bove
UCSF School of Medicine, Department of Neurology, UCSF, San Francisco, CA, USA
15:00
Closing comments from Chairs