Professor, Department of Biomedical Sciences and Scientific Director, Novo Nordisk Foundation Center for Basic Metabolic Research at The Faculty of Health and Medical Sciences, University of Copenhagen.
2010 –> Scientific Director, Novo Nordisk Foundation Center for Basic Metabolic Research, section for Translational Metabolic Physiology at The Faculty of Health and Medical Sciences, UCPH
2007–> Vice chairman Dept. Biomedical Sciences, UCPH
1996 –> Full Professor of Medical Physiology, UCPH
1996 –> Member of the Royal Danish Academy of Science and Letters
1993 –> Member of the Danish Academy for Natural Sciences
The scientific work has been focused on the regulatory peptides of the pancreas and the gut and their importance in the regulation of the functions of the GI-tract and metabolism, with particular focus on blood glucose and appetite regulation, obesity and diabetes. A particular emphasis has been on the role of the incretin hormones of the gut (GLP-1 and GIP). Professor Holst great scientific achievements include the discovery of GLP-1 (glucagon-like peptide 1) as the gut hormone being responsible for the glucose-induced gastrointestinal stimulation of insulin secretion and his subsequent both basic and translational research in this field.
Professor Holst is among the most cited European scientists in his field. He has published approx. 1,590 scientific publications which have been cited more than 52,680 times without self-citation. Currently his papers are cited approx. 3500 times a year and he has an H-index of 124. He has received several highly prestigious international prizes, among them the “Claude Bernard lecture and award” (2005), the Anders Jahre Senior Medical Prize (2013), the Fernström Award in November 2015, and more recently, the Harrington Prize (2017). In early 2016 was awarded with the Advanced ERC Grant for the project “Bypass without Surgery”, a 5-year research grant.